aplicação de insulina em diabéticos.1 . *NPL: Protamina Neutra Lispro; ** NPA: Protamina Neutra Aspart; ***NPH: Protamina Neutra Fonte: A atividade da insulina lispro inicia-se aproximadamente 15 minutos após a . médico e leve a embalagem ou bula do medicamento, se possível. Ligue para. subcutaneously administered insulin lispro 8 units from a study in 12 patients with type 1 diabetes is Subcutaneous Insulin Lispro in Type 1 Diabetes Patients*.

Author: Zololkis Kigaramar
Country: Moldova, Republic of
Language: English (Spanish)
Genre: Spiritual
Published (Last): 28 June 2008
Pages: 310
PDF File Size: 17.22 Mb
ePub File Size: 2.50 Mb
ISBN: 944-5-76858-823-8
Downloads: 80443
Price: Free* [*Free Regsitration Required]
Uploader: Yot

It was first approved for use in the United States inmaking it Includes Humalog side effects, interactions and indications. Cases of buka failure have been reported when pioglitazone was used in combination with insulin, especially in patients with risk factors for development of cardiac heart failure. Within each frequency grouping, adverse lisppro are presented in order of decreasing seriousness.

Changes in insulin strength, manufacturer, type, or method of administration may affect glycemic control and predispose to hypoglycemia [see Warnings and Precautions Date of revision of the text.

Back to top Eli Lilly and Company Limited contact details. Cases of oedema have been reported with insulin therapy, particularly if previous poor metabolic control is improved by intensified insulin therapy. Marketing authorisation holder 8. Excipients This medicinal product contains less than 1 mmol sodium 23 mg per dose, i.

Uncorrected hypoglycaemic or hyperglycaemic reactions can cause loss of consciousness, coma, or death. Instructions for use and handling To prevent the possible transmission of disease, each pen must be used by one patient only, even if the needle is changed.


It is essential to maintain good control of the insulin-treated insulin-dependent or gestational diabetes patient throughout pregnancy. When necessary Humalog can be given soon after meals. Each KwikPen delivers units in steps of insuulina unit.


The patient’s ability to concentrate and react may be impaired as a result of hypoglycaemia.

Insulins have no specific overdose definitions because serum glucose concentrations are a result of complex interactions between insulin levels, glucose availability and other metabolic processes.

Needles are not included. In patients with type 2 diabetes over a wide range of renal function the pharmacokinetic differences between insulin lispro and soluble human insulin were generally maintained and shown to be independent of renal function.

The advisability of driving should be considered in these circumstances. The patient should be given a meal as soon as consciousness is recovered.

Continue typing to refine. Detailed information on this medicinal product is available on the website of the European Medicines Agency http: This medicinal product contains less than 1 mmol sodium 23 mg per dose, i. When administered subcutaneously care should be taken when injecting Humalog to ensure that a blood vessel has not been entered.

Hypersensitivity to the active substance or to any of the excipients listed in section 6. Humalog insulin lispro is used to treat type 1 insulin-dependent diabetes in adults. Healthcare professionals are asked to report any suspected adverse reactions via Ireland: Method of administration Humalog solution for injection should be given subcutaneously.

Name of the medicinal product 2. The time course of action of any insulin may vary considerably in different individuals or at different times in the same individual.

Pioglitazone should be discontinued, if any deterioration in cardiac symptoms occurs. After first use 28 days. Special populations Renal impairment Insulin requirements may be reduced in the presence of renal impairment.

Severe hypoglycaemia may lead to loss of consciousness, and in extreme cases, death. Within muscle tissue this includes increasing glycogen, fatty acid, glycerol and protein synthesis and amino acid uptake, while decreasing glycogenolysis, gluconeogenesis, ketogenesis, lipolysis, protein catabolism and amino acid output. Clinical trials in patients with type 1 and type 2 diabetes have demonstrated reduced postprandial hyperglycaemia with insulin lispro compared to soluble human insulin.


No specific frequency for hypoglycaemia is presented, since hypoglycaemia is a result of both the insulin dose and other factors e. Subcutaneous administration should be in the upper arms, thighs, buttocks, or abdomen. Correction of moderately severe hypoglycaemia can be accomplished by intramuscular or subcutaneous administration of glucagon, followed by oral carbohydrate when the patient recovers sufficiently.

Marketing authorisation number s 9. Skin and subcutaneous tissue disorders.

Hipoglicemiante – Wikipédia, a enciclopédia livre

Humalog may be given shortly before meals. Insulin lispro, sold under the brand name Humalog among others, is a fast acting insulin analog.

Yellow Card Scheme, website: The markings on inxulina insulin syringe will not measure the dose correctly. Hypoglycaemia may occur as a result of an excess of insulin activity relative to food intake and energy expenditure.

In some studies, reduction of nocturnal hypoglycaemia was associated with increased episodes of daytime hypoglycaemia. Patients who fail to respond to glucagon must be given glucose solution intravenously. This rapid onset of activity allows a Humalog injection to be given very close to mealtime.

Search for a drug: Any unused product or waste material should be disposed of in accordance with local requirements. The glucodynamic response to insulin lispro is not affected by renal or hepatic function impairment. Prescription Drug Search Strengths available for Humalog cartridge: This may constitute a risk in situations where these abilities are of special importance e.

Find out more here.